Wednesday, November 9, 2011

What is chromosome?


In the nucleus of each cell, the DNA molecule is packaged in to threat- like structures called chromosome. Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.
Chromosomes are not visible in the cell nucleus not even under microscope when the cell is not dividing. However the DNA that makes up chromosomes become more tightly packed during cell division is then visible under microscope.

Friday, November 4, 2011

DNA Finger Printing

The Chemical structure of everyone,s DNA is same.
The chemical structure of man and animals are also the same.
The Different between animals and within people is also generated by DNA, So how it happens if DNA structure is same...
That happens like this
although the chemical structure of a DNA is same order of the base pairs of DNA is different. This will occur the differences between animals.
every person has different sequence of DNA to identify a person scientists have to recognize this sequence of millions of DNAs so scientists use short method to do that because of repeating pasterns in DNA
This method will not able to recognize people separately but will able to recognize whether the two DNA samples are from same person.

Saturday, October 22, 2011

Micro Biology


Micro biology is a study about living things which are very small and can't observe by unaided eye.
These living things are called as microorganisms and they can observe only with a microscope.
These microorganisms are very useful for human and sometimes it cause diseases. With this label Microbiology i am trying to give some knowledge about micro organisms their formation their activities and uses.
Several scientists involve on doing experiments about microorganisms I will tell about the history of microorganisms with my next blog post

Thursday, September 29, 2011

What is Life?


The entire scientist tried to give a simple definition to life. These scientists were not succeeded according to the knowledge they have gathered they came to know that life can’t define simply. So they compared living and non living things to define life.

1. Living things has an organized structure

When we consider any living thing it is made with organized structure. Atom > Cell > Tissue > like that. Cell is the smallest living thing. It is made with number of atoms and consists with sub cell structures like (mitochondria, ribosome)

2. Living things can involve in reproduction

Every living thing can reproduce. As a living been ends its life in someday they involve in reproduction which can produce another living been which has the same qualities of their parents.

3. Living things will respond to their environment.

Living things can respond to the environment. We know this from the experience we will move to shade if there is too much of sunlight. Plants will wilt if there is no water.

4. Living thins can grow and develop

Living things are growing and developing. This can’t do by non living things.

5. Living things can adapt to the nature

Living things will adapt according to their living places. Mammals live in cold areas have more boozy skin comparing to other mammals.

6. Living things need energy

Every living thing needs energy to continue their lives.

7. Living things can move

Every living thing can move, even a plant. Although we can’t see plants are walking water and nutrients are moving in their xylems.

8. Living things can involve in evolution

9. Living things have biological & chemical reactions inside them.

Saturday, September 24, 2011

What is Biology?


Bio – living Logy- study so studding about living things is simply known as biology. Biology is the basic foundation to even study Medicine. Lot of universities and schools provide the facility of learning biology for students for their higher studies. Biology can divide in to two parts as Zoology and Botany. As I am a undergraduate in Agriculture this blog may focus more in to Botany. What is Zoology? Zoology is the study about animals and botany is the study of Plants. Usually living things can be categorize in to five kingdoms Monera ,Protista ,Fung,i Plantae, Animalia . In Biology we can discuss about these kingdoms. Other than zoology and botany students can study morphology and physiology of living organisms. Students will able to learn about structure of a living organism under morphology and under physiology they will learn about the functions inside the living organisms.

If we think about the history of biology we can’t exactly tell when it began. Our ancestors may get some knowledge about plants and animals living around them and they may gather information about those plants and animals. This may be the beginning of Biology. With the arrival of Greek civilization people has started to search for reasons cause for the result. People started to believe their should be a reason for every effect. This way of thinking made the foundation of science and biology is a branch of science. This science is the science of life. So Biology also developed with science step by step. After people found microscopes to observe micro organism Micro biology also developed as a science. After the invention of electronic microscopes which is more powerful than light microscope people found more about structure of plant and animal cells and about cell division like things. So here with this blog notes I will help you to improve your biological knowledge.

Saturday, January 29, 2011

Topoisomerases and helicases


Topoisomerases are enzymes with both nuclease and ligase activity. These proteins change the amount of supercoiling in DNA. Some of these enzymes work by cutting the DNA helix and allowing one section to rotate, thereby reducing its level of supercoiling; the enzyme then seals the DNA break.[27] Other types of these enzymes are capable of cutting one DNA helix and then passing a second strand of DNA through this break, before rejoining the helix.[96] Topoisomerases are required for many processes involving DNA, such as DNA replication and transcription.[28]

Helicases are proteins that are a type of molecular motor. They use the chemical energy in nucleoside triphosphates, predominantly ATP, to break hydrogen bonds between bases and unwind the DNA double helix into single strands.[97] These enzymes are essential for most processes where enzymes need to access the DNA bases.

DNA-modifying enzymes


Nucleases and ligases

Nucleases are enzymes that cut DNA strands by catalyzing the hydrolysis of the phosphodiester bonds. Nucleases that hydrolyse nucleotides from the ends of DNA strands are called exonucleases, while endonucleases cut within strands. The most frequently used nucleases in molecular biology are the restriction endonucleases, which cut DNA at specific sequences. For instance, the EcoRV enzyme shown to the left recognizes the 6-base sequence 5′-GAT|ATC-3′ and makes a cut at the vertical line. In nature, these enzymes protect bacteria against phage infection by digesting the phage DNA when it enters the bacterial cell, acting as part of the restriction modification system.[94] In technology, these sequence-specific nucleases are used in molecular cloning and DNA fingerprinting.

Enzymes called DNA ligases can rejoin cut or broken DNA strands.[95] Ligases are particularly important in lagging strand DNA replication, as they join together the short segments of DNA produced at the replication fork into a complete copy of the DNA template. They are also used in DNA repair and genetic recombination.[95]